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Mechanism of insulin resistance in obesity: a role of ATP

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 372-382 doi: 10.1007/s11684-021-0862-5

Abstract: Existing hypotheses include inflammation, mitochondrial dysfunction, hyperinsulinemia, hyperglucagonemiaresistance through several mechanisms, such as inhibition of AMPK, induction of mTOR, hyperinsulinemia, hyperglucagonemia

Keywords： type 2 diabetes     energy expenditure     mitochondria     hyperinsulinemia     hyperglucagonemia     AMPK    

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Mechanism of insulin resistance in obesity: a role of ATP

Journal Article